TO RESOLVE:

FUNGAL INFECTIONS
BACTERIAL INFECTIONS

MICROBIAL DEFENSE - Barberry derives from the Oregon Grape root, and may offer microbial defense properties.

General Description

Barberry is an extract produced from the root of Mahonia aquifolium, commonly known as Oregon Grape Root. The Mayo Clinic in 1999 published research proving that chronic sinusitis is caused by an underlying fungus in the sinuses with a superimposed bacterial infection. Only the acute superimposed bacterial infection is eliminated when a patient is treated with a standard pharmaceutical antibacterial; the underlying chronic fungal infection in the sinuses is not addressed.

BARBERRY addresses both the bacterial and fungal infections. Many patients that have asthma and bronchospastic disease have chronic sinusitis and/or chronic bronchitis as an underlying cause. Since BARBERRY addresses the underlying infectious causes so well, it usually helps resolve the bronchospasm and asthma. Many practitioners have also found that atherosclerotic disease appears to be primarily an infectious disease caused by bacteria, fungi and sometimes viruses; those practitioners have found BARBERRY to be very helpful in resolving the infection which then causes atherosclerosis to diminish and resolve. BARBERRY effectively treats Chlamydia pneumonia, mycoplasma, many herpes viruses of different types and mucor; peer-reviewed literature states that all of these are known to contribute to atherosclerotic disease.

Some Reported Medicinal Properties

ANTIOXIDANT

ANTIMUTAGENIC

ANTIPSORIATIC

ANTIHYPERTENSIVE

ANTI-INFLAMMATORY

ANTIFUNGAL

ANTIMICROBIAL

ALTERATIVE

CHOLAGOGUE

ANTIPROLIFERATIVE

ASTRINGENT

STOMACHIC

Medical Conditions [peer-reviewed journals]

ATOPIC DERMATITIS

Klövekorn, W., Tepe, A., & Danesch, U. (2007). A randomized, double-blind, vehicle-controlled, half-side comparison with a herbal ointment containing Mahonia aquifolium, Viola tricolor and Centella asiatica for the treatment of mild-to-moderate atopic dermatitis. International Journal of Clinical Pharmacology and Therapeutics, 45(11), 583-591. Full Article

PSORIASIS

Bernstein, S., Donsky, H., Gulliver, W., Hamilton, D., Nobel, S., & Norman, R. (2006). Treatment of mild to moderate psoriasis with Relieva, a Mahonia aquifolium extract—a double-blind, placebo-controlled study.American Journal of Therapeutics, 13(2), 121-126. Full Article

Wiesenauer, M., & Lüdtke, R. (1996). Mahonia aquifolium in patients with Psoriasis vulgaris—an intraindividual study. Phytomedicine, 3(3), 231-235. Full Article

ATOPIC DERMATITIS

Donsky, H., & Clarke, D. (2007). Relieva, a Mahonia aquifolium extract for the treatment of adult patients with atopic dermatitis. American Journal of Therapeutics, 14(5), 442-446. Full Article

CANCER

Damjanović, A., Zdunić, G., Šavikin, K., Mandić, B., Jadranin, M., Matić, I. Z., & Stanojković, T. (2016). Evaluation of the anti-cancer potential of Mahonia aquifolium extracts via apoptosis and anti-angiogenesis.Bangladesh J Pharmacol, 11, 741-749. Full Article

Čerňáková, M., Košt'álová, D., Kettmann, V., Plodová, M., Tóth, J., & Dřímal, J. (2002). Potential antimutagenic activity of berberine, a constituent of Mahonia aquifolium. BMC complementary and alternative medicine, 2(1), 2. Full Article

Medicinal Properties [peer-reviewed journals]

ANTIOXIDANT

Coklar, H., & Akbulut, M. (2017). Anthocyanins and phenolic compounds of Mahonia aquifolium berries and their contributions to antioxidant activity. Journal of Functional Foods, 35, 166-174. Full Article

Pyrkosz-Biardzka, K., Kucharska, A. Z., Sokół-Łętowska, A., Strugała, P., & Gabrielska, J. (2014). A comprehensive study on antioxidant properties of crude extracts from fruits of Berberis vulgaris L., Cornus mas L. and Mahonia aquifolium Nutt. Polish Journal of Food and Nutrition Sciences, 64(2), 91-99. Full Article

Kumaraswamy, M. V., & Satish, S. (2008). Free radical scavenging activity and lipoxygenase inhibition of Woodfordia fructicosa Kurz and Betula utilis Wall. African Journal of Biotechnology, 7(12), 2013-2016. Full Article

Račková, L., Májeková, M., Košt’álová, D., & Štefek, M. (2004). Antiradical and antioxidant activities of alkaloids isolated from Mahonia aquifolium. Structural Aspects. Bioorganic & Medicinal Chemistry, 12(17), 4709-4715. Full Article

Müller, K., & Ziereis, K. (1994). The antipsoriatic Mahonia aquifolium and its active constituents; I. Pro-and antioxidant properties and inhibition of 5-lipoxygenase. Planta Medica, 60(05), 421-424. Full Abstract

ANTIFUNGAL

Volleková, A., Košt'álová, D., Kettmann, V., & Tóth, J. (2003). Antifungal activity of Mahonia aquifolium extract and its major protoberberine alkaloids. Phytotherapy Research, 17(7), 834-837. Full Article

ANTI-INFLAMMATORY

Andreicuţ, A. D., Parvu, A. E., Moț, A. C., Parvu, M., FISCHER-FODOR, E. V. A., VASILE FELDRIHAN, A. F., ... & IRIMIE, A. (2018). Anti-inflammatory and antioxidant effects of Mahonia aquifolium leaves and bark extracts. Farmacia, 66(1). Full Article

ANTIMUTAGENIC ACTIVITY

Čerňáková, M., Košt'álová, D., Kettmann, V., Plodová, M., Tóth, J., & Dřímal, J. (2002). Potential antimutagenic activity of berberine, a constituent of Mahonia aquifolium. BMC Complementary and Alternative Medicine, 2(1), 2. Full Article

ANTIMICROBIAL

Rohrer, U., Kunz, E. M., Lenkeit, K., Schaffner, W., & Meyer, J. (2007). Antimicrobial activity of Mahonia aquifolium and two of its alkaloids against oral bacteria. Schweizer Monatsschrift fur Zahnmedizin= Revue mensuelle suisse d'odonto-stomatologie= Rivista mensile svizzera di odontologia e stomatologia, 117(11), 1126-1131. Full Abstract

Slobodníková, L., KoSt'álová, D., Labudová, D., Kotulová, D., & Kettmann, V. (2004). Antimicrobial activity of Mahonia aquifolium crude extract and its major isolated alkaloids. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 18(8), 674-676. Full Article

ANTITUSSIVE

Kardošová, A., Malovı́ková, A., Pätoprstý, V., Nosal'Ova, G., & Matáková, T. (2002). Structural characterization and antitussive activity of a glucuronoxylan from Mahonia aquifolium (Pursh) Nutt. Carbohydrate Polymers, 47(1), 27-33. Full Article

IMMUNOMODULATING

Galle, K., Müller-Jakic, B., Proebstle, A., Jurcic, K., Bladt, S., & Wagner, H. (1994). Analytical and pharmacological studies on Mahonia aquifolium. Phytomedicine, 1(1), 59-62. Full Article

Patient Reports

"Once I turned 21, I was crippled by chronic sinusitis. 7 years of my life were spent sick, on antibiotics and steroids. Barberry changed all that and wiped out my sinus infections and I'm now healthy and living my life to the fullest!"-M.Z.

“I don't know what you do to this herb but it's the best barberry I've ever seen. If anyone wants barberry I say don't waste your money on any other brand. I promise you they're not as good. I know. I tried them all.” – M.S

“This has been a great extract to use for P.A.N.D.A.S and it has lessened the severity of my daughter's tics.” – P.N

"Barberry helped me with getting over a urinary tract infection. It lasted almost 2 months. The meds that the doctor gave me didn't work, but after one full day of Barberry, it was GONE. " -O.M.

Dosage Information

15 to 30 drops in 4 oz. of water 30 minutes before a meal twice daily.

Safety Information

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Barberry did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary.

PROPRIETARY WHOLE HERB EXTRACTION PROCESS - Highly bioavailable liquid for improved absorption. Nutramedix’s unique enhancement process optimizes the whole herb for a more powerful broad-spectrum extract.

FROM NATURE - Our products are sourced from nature’s richest botanical resources, primarily Peru and the Amazon Rainforest.

FEEL THE DIFFERENCE - Put 15 to 30 drops in 4 oz. of water and wait one minute before drinking. Take twice daily (30 min. before meals) or as directed by your physician. Do not use if pregnant or nursing. Shake well before each use.

OVER 20 YEARS OF NUTRACEUTICAL INNOVATION - Founded in 1993, Nutramedix supplies highly bioavailable nutritional supplements to health care professionals and consumers. A majority of Nutramedix profits are donated to charitable organizations.

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